Structural formula

　　Common name Cyhalofop-butyl

　　Product name Cyhalofop-butyl

　　CAS number 122008-85-9 Molecular weight

　　357.375

　　Density 1.2±0.1 g/cm3

　　Boiling point 449.1±45.0 ? at 760 mmHg

　　Molecular formula C20H20FNO4

　　Melting point 49.5ºC

　　Flash point 225.4±28.7 °C

Symbol

　　GHS07, GHS0 9

　　Signal word Warning

　　Uses

　　Cyhalofop-butyl is a post-emergent herbicide. Cyhalofop-butyl inhibits the biosynthesis of acetyl-CoA carboxylase (ACCase).

　　Cyhalofop-butyl nameProduct name

　　cyhalofop-butyl

　　Alias ??(R)-2-[4(4-cyano-2-fluorophenoxy)phenoxy]-butylpropionate

　　Cyhalofop-butyl Biological Activity

　　Description Cyhalofop-butyl is a post-emergent herbicide. Cyhalofop-butyl inhibits the biosynthesis of acetyl-CoA carboxylase (ACCase).

　　Physical and chemical properties Density 1.2±0.1 g/cm3 Boiling point 449.1±45.0 °C at 760 mmHg Melting point 49.5ºC Molecular formula C20H20FNO4 Molecular weight 357.375 Flash point 225.4±28.7 °C Accurate mass 357.137634 PSA 68.55000 LogP 4.40 Appearance Solid; White to Almost white powder to lump vapor pressure 0.0±1.1 mmHg at 25°C refractive index 1.551 storage conditions 0-6°C water solubility soluble in: methanol molecular structure 1, molar refractive index: 93.86

　　2. Molar volume (cm3/mol): 294.2

　　3. Isotonic specific volume (90.2K): 775.2

　　4. Surface tension (dyne/cm): 48.1

　　5. Dielectric constant: None available

　　6. Polarizability (10-24cm3): 37.21

　　7. Single isotope mass: 357.137636 Da

　　8. Nominal mass: 357 Da

　　9. Average mass: 357.3755 Da

　　Computational Chemistry

　　1. Hydrophobic parameter calculation reference value (XlogP): 4.8

　　2. Number of hydrogen bond donors: 0

　　3. Number of hydrogen bond acceptors: 6

　　4. Number of rotatable chemical bonds: 9

　　5. Number of tautomers: None

　　6. Topological molecular polar surface area 68.6

　　7. Number of heavy atoms: 26

　　8. Surface charge: 0

　　9. Complexity: 483

　　10. Number of isotope atoms: 0

　　11. Determine the number of atomic stereocenters: 1

　　12. Number of uncertain atomic stereocenters: 0

　　13. Determine the number of stereocenters of chemical bonds: 0

　　14. Uncertain number of chemical bond stereocenters: 0

　　15. Number of covalent bond units: 1

　　Cyhalofop-butyl MSDS

　　1.1 Product identifier

　　: Cyhalofop-butyl

　　chemical common name or trade name

　　1.2 Other methods of identification

　　Butyl (R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propionate

　　1.3 Relevant identification USES OF THE SUBSTANCE OR MIXTURE AND USES ADVISED UNDERSTANDING

　　For research purposes only and not for use as a pharmaceutical, home remedy or for any other purpose.

　　Module 2. Hazard overview

　　2.1 GHS classification

　　Acute toxicity, Oral (Category 4)

　　Acute toxicity, Dermal (Category 5)

　　Acute aquatic toxicity (Category 1)

　　2.2 GHS labeling elements, including precautionary statements

　　Hazard type pictogram

　　signal Word Warning

　　Hazard Statements

　　H302 Harmful if swallowed.

　　H313 may be harmful in contact with skin.

　　H400 is extremely toxic to aquatic life.

　　Warning Statement

　　Prevention

　　P264 Clean skin thoroughly after handling.

　　P270Do not eat, drink or smoke while using this product.

　　P273 Avoid release into the environment.

　　Actions

　　P301 + P312 If swallowed: If you feel unwell, call a poison center or see a doctor.

　　P312 If you feel unwell, call a detoxification center or doctor.

　　P330 rinse mouth.

　　P391Catch spillage.

　　Disposal

　　P501 Dispose of contents/container to an approved waste treatment plant.

　　2.3 Other Hazardous Substances - None

　　Module 3. Composition/Composition Information

　　3.1 Substance

　　Alias: Butyl (R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propionate Molecular

　　formula: C20H20FNO4

　　Molecular weight: 357.38 g/mol

　　Ingredient concentration

　　Cyhalofopbutyl

　　Module 4. First aid measures

　　4.1 Description of necessary first aid measures

　　General advice

　　Consult a doctor. Show this safety data sheet to the doctor on site.

　　If inhaled

　　If inhaled, move victim to fresh air. If breathing stops, give artificial respiration. Ask a doctor.

　　In case of skin contact

　　wash with soap and plenty of water. Ask a doctor.

　　In case of eye contact

　　flush eyes with water as a precaution.

　　If Ingested

　　Never give anything by mouth to an unconscious person. Rinse mouth with water. Ask a doctor.

　　4.2 Most important symptoms and effects, both acute and delayed

　　To the best of our knowledge, the chemical, physical and toxicological properties have not been completely studied.

　　4.3 Instructions for prompt medical treatment and any special treatment needed

　　No data available

　　Module 5. Firefighting measures

　　5.1 Fire-extinguishing media

　　Fire-fighting methods and fire-extinguishing media

　　Use water spray, alcohol-resistant foam, dry powder or carbon dioxide to extinguish fires.

　　5.2 Special hazards arising from the substance or mixture

　　Carbon oxides, nitrogen oxides, hydrogen fluoride

　　5.3 Precautions for fire-fighters

　　If necessary, wear self-contained breathing apparatus for fire-fighting.

　　5.4 Further information

　　No data available

　　Module 6. Accidental release measures

　　6.1 Personal precautions, protective equipment and emergency procedures

　　Use personal protective equipment. Prevent the generation of dust. Avoid breathing vapors, aerosols or gases. Ensure adequate ventilation.

　　Evacuate personnel to a safe area. Avoid breathing dust.

　　6.2 Environmental precautions

　　Take measures to prevent further leakage or spillage under safe conditions. Do not allow product to enter drains.

　　Prevent emissions to the surrounding environment.

　　6.3 Methods and materials to contain and clean up spills

　　Collect and dispose of spills without creating dust. Sweep and shovel away. Store in suitable closed disposal containers.

　　6.4 Reference to other sections

　　Please refer to Section 13 for discard processing.

　　Module 7. Handling and Storage

　　7.1 Precautions for safe handling

　　Avoid contact with skin and eyes. Prevent dust and aerosol generation.

　　Where dust is generated, provide appropriate exhaust equipment. General fire protection measures.

　　7.2 Conditions for safe storage, including any incompatibilities

　　Store in a cool place. Keep the container tightly closed and store in a dry and ventilated place.

　　7.3 Specific uses

　　No data available

　　Module 8. Exposure controls/personal protection

　　8.1 Control parameters

　　Maximum permissible concentration

　　There are no known national exposure limits.

　　8.2 Exposure controls

　　Appropriate technical controls

　　Handle in accordance with rules of industrial hygiene and safe use. Wash your hands before breaks and at the end of work.

　　Personal protective equipment

　　Eye/face protection

　　Safety glasses with side shields comply with EN166 requirements. Please use

　　equipment tested and approved by official standards such as NIOSH (USA) or EN 166 (EU) to protect your eyes.

　　Skin Protection

　　Gloves must be inspected before use.

　　Please use appropriate methods to remove gloves (do not touch the outer surface of the gloves) and avoid any skin contact with this product.

　　After use, please handle contaminated gloves carefully in accordance with relevant laws and regulations and effective laboratory procedures. Please wash and Blow-dry your hands

　　. The protective gloves chosen must comply with EU directive 89/686/EEC and the EN 376 standard derived from it.

　　Body protection

　　Full set of work clothes against chemical agents. The type of protective equipment must be selected according to the concentration and content of dangerous substances in the specific workplace.

　　Respiratory protection

　　If exposed to harmful environments, please use type P95 (US) or P1 (EU, UK)

　　143) Particulate respirator. If you need a higher level of protection, please use OV/AG/P99 type (US) or ABEK-P2 type (EU UK 143)

　　gas cans.

　　Respirators use respirators and parts that have been tested and passed government standards such as NIOSH (US) or CEN (EU).

　　Module 9. Physicochemical Properties

　　9.1 Information on basic physicochemical properties

　　a) Appearance and properties

　　Shape: Crystalline

　　Color: White

　　b) Odor

　　Characteristic

　　c) Odor critical value

　　No data available

　　d) pH value

　　6.7 at 23 °C

　　e) Melting point/freezing point

　　48 - 50 °C

　　f) Initial boiling point and boiling range

　　> 270 °C

　　g) Flash point

　　122 °C - closed cup

　　h) Evaporation rate

　　No data availablei

　　) Flammability (solid, gas)

　　No data availablej

　　) High /Low flammability or explosive limits No data available

　　k) Vapor pressure

　　530 hPa

　　l) Relative vapor density

　　No data available

　　m) Relative density

　　1.172 g/cm3 at 20 °C

　　n) Water solubility

　　0.00044 g/l at 20 °C

　　o) Log value of the octanol/water partition coefficient

　　Log value of the octanol-water partition coefficient: 3.316 at 25 °C

　　p) Autoignition temperature

　　No data availableq

　　) Decomposition temperature

　　No data availabler

　　) Viscosity

　　No data available

　　Module 10. Stability and reactivity

　　10.1 Reactivity

　　No data available

　　10.2 Chemical stability

　　No data available

　　10.3 Possibility of hazardous reactions

　　No data available

　　10.4 Conditions to avoid Contact

　　no data

　　available 10.5 Incompatible materials

　　Water, acids and alkalis

　　10.6 Danger Decomposition products of

　　Other decomposition products - No data available

　　Module 11. Toxicological information

　　11.1 Information on toxicological effects

　　Acute

　　toxicity LD50 Oral - Rat - 1,611.7 mg/kg

　　LC50 Inhalation - Rat - > 5.63 mg/l

　　LC50 LD50) Dermal - Rat - > 2,000 mg/kg

　　Skin corrosion/irritation

　　Serious eye damage/eye irritation

　　Eye - Rabbit -

　　Remarks: Mild irritation

　　Respiratory or skin sensitization

　　Guinea pig -

　　Remarks: Not expected

　　Germ cell mutagenesis

　　No data available

　　Carcinogenicity

　　IARC:

　　There are no components in this product at levels greater than or equal to 0.1% that have been identified by IARC as possible or definite human carcinogens.

　　Reproductive toxicity

　　No data available

　　Specific target organ systemic toxicity (single exposure)

　　No data available

　　Specific target organ systemic toxicity (repeated exposure)

　　No data available

　　Aspiration hazard

　　No data available

　　Potential health effects

　　Inhalation May be harmful if inhaled. May cause respiratory irritation.

　　Harmful to human body if swallowed.

　　Skin may be harmful if absorbed through the skin. May cause skin irritation.

　　Eyes May cause eye irritation.

　　Signs and Symptoms Following Exposure

　　To the best of our knowledge, the chemical, physical and toxicological properties have not been completely studied.

　　Additional information

　　Registration of toxic effects of chemical substances: No data available

　　Module 12. Ecological information

　　12.1 Toxicity

　　Toxicity to fish LC50 - Oncorhynchus mykiss (red trout) - > 0.49 mg/l

　　LC50 - Lepomis macrochirus (bluegill sunfish) - > 0.76 mg/l

　　toxicity to algae Note: Highly toxic to algae.

　　12.2 Persistence and degradability

　　Biodegradability Aerobic Exercise

　　Remarks: According to the results of the biodegradation test, this product is easily degradable.

　　12.3 Bioaccumulation potential

　　No data available

　　12.4 Mobility in soil

　　No data available

　　12.5 Evaluation of results for PBT and vPvB

　　No data available

　　12.6 Other adverse effects

　　Very toxic to aquatic life.

　　Module 13. Disposal

　　13.1 Waste disposal methods

　　Product

　　Hand in remaining and unrecovered solution to a disposal company. Contact a professional licensed waste disposal facility to dispose of this material.

　　Miscible or mixed with flammable solvents, burned in a chemical incinerator equipped with post-combustion treatment and scrubbing. Contaminated

　　packaging

　　is discarded as unused product.

　　Module 14. Transport information

　　14.1 UN number

　　European Land Transport Risk Regulation: 3077 International Maritime Transport Risk Regulation: 3077 International Air Transport Risk Regulation: 3077

　　14.2 Name specified by the United Nations (UN)

　　European Land Transport Risk Regulation: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, NOS (Cyhalofopbutyl)

　　International Maritime hazard regulations: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, NOS ( Cyhalofopbutyl

　　) 9 14.4 Package group EuroRUL: III IMDG: III IMDG: III 14.5 Environmental hazard EuroRUL: Yes IMDG Maritime contaminants: Yes IMDG: Yes 14.6 To the user Special precautions for further information : Dangerous goods are individually packaged, liquids are more than 5 liters or solids are more than 5 kilograms. Each independent package and the combined independent inner package must have EHS on the outer package.

　　Labeling (according to European ADR Regulation 2.2.9.1.10, IMDG Regulation 2.10.3),

　　Module 15 - Regulatory Information

　　N/A

　　Module 16 - Additional Information

　　N/A

　　Safety Information

　　Symbol

　　GHS07, GHS09

　　Signal Word Warning

　　Hazard Statement H302-H400

　　Precautionary Statement P273

　　Personal Protective Equipment dust mask type N95 (US); Eyeshields; Gloves

　　Hazard Code (Europe) Xn, N

　　Risk Statement (Europe) 22- 50

　　Safety Statement (Europe) S22-S24/25

　　Dangerous Goods Transport Code UN 3077 9 / PGIII

　　WGK Germany 3

　　Customs Code 2926909039